Graft for promoting autogenous tissue growth
AssigneePurdue Research Foundation
InventorsStephen F. Badylak, Leslie A. Geddes, K. Donald Shelbourne, Gary C. Lantz, Arthur C. Coffey
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Abstract
Surgical repair of diseased or damaged endogenous connective tissue can be accomplished using a tissue graft formed from a delaminated segment of intestinal tissue. The tissue graft comprises the intestinal tunica submucosa and basilar mucosa tissue delaminated from the tunica muscularis and the luminal portion of the tunica mucosa. The graft can be conditioned by stretching and formed as a multilayer composition for high tensile strength and resistance to tearing at its points of attachment to existing physiological structures.
Claims5
A method for promoting autogenous regrowth and healing of damaged or diseased tissues selected from the group consisting of bone, ligaments, tendons, muscle and cartilage, said method comprising the step of surgically repairing said structures by attachment of a tissue graft, said graft formed from a segment of intestinal tissue of a warm-blooded vertebrate, said segment comprising the tunica submucosa and basilar tissue of the tunica mucosa, said tunica submucosa and basilar tissue being delaminated from the tunica muscularis and the luminal portion of the tunica mucosa of said segment of intestinal tissue.
A method for surgical repair of diseased or damaged endogenous tissue connecting first and second physiological structures selected from the group consisting of bone, ligament, tendon, cartilage and muscle, said method comprising the step of attaching said first and second structures to opposite end portions or opposite lateral portions of a tissue graft material comprising the tunica submucosa and basilar tissue of the tunica mucosa of a segment of intestinal tissue of a warm-blooded vertebrate, said tissue graft material being delaminated from the tunica muscularis and the luminal portion of the tunica mucosa of said intestinal tissue.
Dependencies are inferred from the claim text.