Size separation of particles contained within a material by the use of nonaqueous hydrodynamic chromatography
AssigneeThe Dow Chemical Company
InventorsMartin A. Langhorst, Joseph B. Henry
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Abstract
A method is disclosed for determining the distribution according to size of particles which make up a noncontinuous phase dispersed within a matrix which is not completely soluble in an aqueous solution. The method involves dissolving the matrix containing the particles in an essentially nonaqueous liquid causing the particles to be suspended. The suspension is then eluted through a separating medium which sorts the particles according to size. A detector monitors the effluent from the separating medium and creates a record of the data. This record is then compared to data obtained from known standards in order to estimate the size distribution in the sample.
Claims17
A method for determining the distribution according to size of a sample of various sized particles, comprising the steps of:
- (a) dispersing the particles in an essentially nonaqueous liquid thereby forming a mixture;
- (b) adding a controlled amount of the mixture to an essentially nonaqueous carrier liquid;
- (c) eluting the carrier liquid containing the mixture through a separating medium effective for sorting the particles according to size wherein the largest particles are eluted first and the smallest particles are eluted last;
- and
- (d) monitoring the effluent from the separating medium by measuring and recording a signal representing a physical property of the effluent that is responsive to the concentration of particles in the effluent.
Dependencies are inferred from the claim text.