Implantable biomedical sensor device, suitable in particular for measuring the concentration of glucose

A biomedical sensor device for assaying in vitro a presence and/or concentration of physiological substances comprising:

• a miniaturized electronic responder responsive to an electromagnetic interrogation field for contactlessly exchanging binary coded information with a transmitter/receiver;
• a closed housing of bio-compatible material having at least one wall, said responder being disposed in said closed housing;
• a work electrode passing through said at least one wall of said housing and comprising an outer part outside of said housing, a membrane having at least one surface, hollow fibers in said membrane extending transversely to said at least one surface of said membrane and having internal walls and ends thereon, a coating of conductive polymer on said internal walls, and a redox enzyme disposed in said hollow fibers;
• a processing device in said housing for receiving signals from maid work electrode in operation and converting said signals to binary signals;
• electrical connection means between one of said ends of said hollow fibers and said processing device for conducting said signals from said work electrode to said processing device;
• a counter-electrode extending through said at least one wall of said housing and having an outer part outside of said housing;
• and
• electrical connection means for connecting said counter-electrode end said processing device.