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US 5,367,080 AGranted
Complexing agents and targeting radioactive immunoreagents useful in therapeutic and diagnostic imaging compositions and methods
AssigneeSterling Winthrop Inc.
InventorsJohn L. Toner, David A. Hilborn, Bruce J. Murray, Timothy Z. Hossain
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Abstract
A targeting radioactive immunoreagent comprising a compound having the structure ##STR1##
Claims7
A compound having the structure ##STR115## wherein R.sup.1 represents hydrogen, alkyl, alkoxy, alkylthio, alkylamino, alkylformamido, phenyl, phenoxy, or a protein reactive group;
- R.sup.2 represents hydroxy, carboxy, hydroxyalkyl, carbonyliminodiacetic acid, methyleneiminodiacetic acid, methylenethioethyleneiminodiacefic acid, hydrazinylylidenediacetic acid, or a salt of such acids;
- R.sup.3 represents hydrogen, alkyl, alkoxy, alkylthio, alkylamino, alkylformamido, phenyl, phenoxy, or a protein reactive group;
- R.sup.5 represents alkyl or alkoxy;
- and
- R.sup.6 represents a amino, isothiocyanato, thiocarbazido or thiosemicarbazido.
2 more elements
A compound having the structure ##STR116##
Dependencies are inferred from the claim text.