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US 5,364,781 AGranted
Process for preparing daunorubicin
AssigneeFarmitalia Carlo Erba S.p.A.
InventorsCharles R. Hutchinson, Krishna M. Madduri, Francesca Torti, Anna L. Colombo
Life of this patent
Estimating the term…
Abstract
The ability to convert carminomycin to daunorubicin can be conferred on a host by transforming the host with a recombinant vector comprising a DNA having the configuration of restriction sites shown in FIGS. 2, 3 & 4 and nucleotide sequence shown in FIG. 3 of the accompanying drawings or a restriction fragment derived therefrom containing a gene coding for carminomycin 4-O-methyltransferase.
Claims1
An isolated and purified carminomycin 4-O-methyl transferase consisting essentially of the amino acid sequence:
- (SEQ ID NO:
- 2) ##STR2##
Dependencies are inferred from the claim text.