Back to results
US 5,362,654 AGranted
Self-contained quantitative assay
AssigneeSangStat Medical Corporation
InventorPhilippe Pouletty
Life of this patent
Estimating the term…
Abstract
Methods and device are provided where a device comprising an absorbing nib, an external deformable container and an internal container having a frangible barrier are provided, where the nib and internal container comprise reagents which are interactive with a sample for measuring an analyte.
Claims11
A collector-diluter-dispenser device useful for processing a sample for a diagnostic assay and quantitatively measuring a sample volume, said device comprising:
- a compressible tube enclosed at one end;
- a cover mounted over the open end of said tube and comprising at least one aperture;
- a liquid medium in said tube;
- a first frangible barrier separating said medium from said aperture;
- at least one absorbent nib in said tube and extending through said aperture, said nib comprising means for preventing said nib to pass through said aperture, providing substantially quantitative release of said sample into said liquid medium for allowing for quantitative determination of an analyte in said sample;
- and
- a second frangible barrier supporting said nib to maintain said nib extending through said aperture, wherein said first and second frangible barriers may be the same.
4 more elements
A collector-diluter-dispenser device useful for processing a sample for a diagnostic assay and quantitatively measuring a sample volume, said device comprising:
- a compressible tube enclosed at one end;
- a cover mounted over the open end of said tube and comprising at least one aperture;
- a liquid medium in said tube;
- a first frangible barrier separating said medium from said aperture;
- at least one absorbent nib in said tube and extending through said aperture, said nib comprising means for preventing said nib to pass through said aperture and impregnated with at least one reagent useful in the determination of an analyte, providing substantially quantitative release of said sample into said liquid medium for allowing for quantitative determination of an analyte in said sample;
- and
- a second frangible barrier supporting said nib to maintain said nib extending through said aperture, wherein said first and second frangible barriers may be the same.
4 more elements
Dependencies are inferred from the claim text.