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AssigneeG. D. Searle & Co.
InventorsDonald W. Hansen, Jr., Karen B. Peterson
Estimating the term…
The present invention provides substituted dibenzoxazepine and dibenzthiazepine compounds of Formula I: ##STR1## which are useful as analgesic agents for the treatment of pain, and for prostaglandin-E.sub.2 mediated diseases, pharmaceutical compositions comprising a therapeutically-effective amount of a compound of Formula I in combination with a pharmaceutically-acceptable carrier, a method for eliminating or ameliorating pain in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal, and a method for treating prostaglandin-E.sub.2 mediated diseases in an animal comprising administering a therapeutically-effective amount of a compound of Formula I to the animal.
A compound having the structure:
A compound having the structure:
A compound having the structure:
A compound having the structure:
A compound having the structure:
A compound having the structure:
A compound having the structure:
A compound having the structure:
A compound having the structure:
A compound having the structure:
A compound having the structure:
A compound having the structure:
A compound having the structure:
A compound having pharmacological activity, wherein the compound is:
A pharmaceutical composition comprising a pharmaceutically-acceptable carrier and a therapeutically-effective amount of a compound, wherein the compound is:
A method for treating pain in an animal comprising administering to said animal a therapeutically-effective amount of a compound, wherein the compound is:
A method for treating diseases responsive to prostaglandin-E.sub.2 antagonists in an animal comprising administering to said animal a therapeutically-effective amount of:
Dependencies are inferred from the claim text.