Water dispersion containing ultrafine particles of organic compounds
AssigneesResearch Development Corporation of Japan, Stanley Electric Co., Ltd.
InventorHideki Toyotama
Life of this patent
Estimating the term…
Abstract
A water-dispersible condensate of water-insoluble ultrafine particles of medicine or hormones having a particle size of at largest 4 .mu.m prepared by the steps of heating the medicine or hormone in a vacuum vessel at a temperature of 30.degree. C. higher than the boiling point and at a pressure between 0.01 Torr and 10 Torr to evaporate the medicine or hormone and condensing the medicine or hormone on a recovery plate to obtain the condensate.
Claims1
A water dispersion consisting of water and water-insoluble ultrafine particles consisting of a medicine dispersed in the water and having a particle size of at largest 4 .mu.m, wherein said ultrafine particles are prepared by the steps of:
- (a) heating said medicine in a vacuum vessel at a temperature of 30.degree. C. higher than the boiling point thereof while controlling a pressure of inert gas in the vessel between 0.01 Torr and 10 Torr to evaporate said medicine;
- and
- (b) condensing the resulting vapor of said medicine on a recovery plate in the vessel to obtain a condensate consisting of said water-insoluble ultrafine particles of medicine to be dispersed in water;
- wherein said medicine is selected from the group consisting of .alpha.-bromoisovaleroylurea, barbital, phenobarbital, phenobarbital sodium, phenytoin, carbamazephine, haloperidol, diazepam, chlormezanone, phenacetin, acetaminophene, aspirin, ethenzamide, phenylbutazone, indomethacin, mepirizole, probenecide, digitoxin, sulfamonomethoxine, tolubatamide, chloramphenicol, ethyl hydroxybenzoate, vitamin B.sub.13, cortisone acetate, predonisone, anthracene, pyrene, metal phthalocyanine, merocyanine, ferrocene and carbazole.
Dependencies are inferred from the claim text.