Back to results
US 5,354,472 AGranted
Anion exchange materials comprised of derivatized cellulose-polyester composites
AssigneeCobe Cardiovascular, Inc.
InventorsMarc Voorhees, Ben F. Brian, III, Lloyd Forrestal
Life of this patent
Estimating the term…
Abstract
A novel biocompatible anion exchange membrane is prepared by reacting the hydroxyl groups of a chromatographic support material with a polyester-cellulose solution containing glycidyl trimethyl ammonium chloride and bis glycidyl polyethylene oxide.
Claims25
A biocompatible anion exchange material comprised of:
- polyester;
- cellulose comprising a plurality of hydroxyl groups, said cellulose and polyester forming a heat entangled nonwoven blend;
- quaternary ammonium functionalities covalently attached to said cellulose at least some of said hydroxyl groups;
- and
- polyethylene oxide covalently attached to said cellulose at least some of said hydroxyl groups.
2 more elements
A method for preparing biocompatible anion exchange materials comprising:
- placing a support comprised of surface hydroxyl groups in a solution containing GPEO and GTMAC;
- and
- drying the support material.
A method for removing anionic species from a bodily fluid comprising:
- contacting said bodily fluid with an anionic exchange material, wherein said material is comprised of a heat entangled nonwoven blend of polyester and cellulose, having quaternary ammonium functionalities covalently attached to said cellulose and polyethylene oxide functionalities covalently attached to said cellulose.
A method for preparing biocompatible anion exchange materials comprising:
- placing a heat entangled nonwoven blend comprised of polyester and cellulose in a solution containing GPEO and GTMAC capable of covalently attaching polyethylene oxide and quaternary ammonium functionalities to said cellulose;
- and
- drying the support.
A method for removing anionic species from a bodily fluid comprising:
- contacting said bodily fluid with an anionic exchange material, wherein said material is comprised of a composite polyester and cellulose heat entangled nonwoven blend having quaternary ammonium functionalities covalently attached to said cellulose and polyethylene oxide functionalities covalently attached to said cellulose, said quaternary ammonium functionalities and polyethylene oxide functionalities formed by placing said composite support material having surface hydroxyl groups in a solution containing GPEO and GTMAC, and drying said support.
Dependencies are inferred from the claim text.