# US 5,352,686 A · Method for producing an orexigenic effect

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- Number: US 5,352,686 A
- Document ID: US5352686A
- Status: Granted
- Kind: A
- Application number: 08/097,097
- Filed: 1993-07-26
- Granted: 1994-10-04
- Earliest claimed: 1991-08-09
- Assignees: Merrell Dow Pharmaceuticals Inc.
- Inventors: John T. Burke
- Web page: https://patentgrep.com/patent/US5352686A

## CPC

- A61K 31/47: Quinolines; Isoquinolines
- A61K 31/445: Non condensed piperidines, e.g. piperocaine
- A61P 3/04: Anorexiants; Antiobesity agents
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The present invention is directed to the use of esters of hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-one and hexahydro-8-hydroxy-2,6-methano-2H-quinolizines in the manufacture of a medicament for producing an orexigenic effect.

## Claims

### Claim 1

A method for producing an orexigenic effect comprising administering to a patient in need thereof an orexigenic amount of endo-hexadro-8-(3-indolycarbonyloxy)-2,6-methano-2H-quinolizin-3(4H-one.

### Claim 2

A method for producing an orexigenic effect comprising administering to a patient in need thereof an orexigenic amount of endo-8-(3-indolylcarbonyloxy)-2,6-methanooctahydro-2H-quinolizin-3ol.