Ionophore containing liposomes for ultrasound imaging
OwnerEvan C. Ungerinventor
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Abstract
Liposomes suitable as ultrasound contrast agents which contain media of various types including gases, gaseous precursors activated by pH, temperature or pressure, as well as other solid or liquid contrast enhancing agents, are described. Methods of using the same as ultrasound contrast agents are also disclosed. The present invention also comprises novel methods for synthesizing liposomes having encapsulated therein gases.
Claims18
A contrast agent for ultrasonic imaging which comprises an ionophore-containing liposome having encapsulated therein a pH-activated gaseous precursor.
A contrast agent for ultrasonic imaging which comprises a liposome having encapsulated therein a solid contrast enhancing agent selected from the group consisting of magnetite and solid iodine particles or a liquid contrast enhancing agent selected from the group consisting of solubilized iodinated compounds.
Dependencies are inferred from the claim text.