# US 5,349,070 A · Salicylic acid-maltol conjugates

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- Number: US 5,349,070 A
- Document ID: US5349070A
- Status: Granted
- Kind: A
- Application number: 07/971,832
- Filed: 1993-02-19
- Granted: 1994-09-20
- Earliest claimed: 1993-02-19
- Inventors: Byung H. Han
- Web page: https://patentgrep.com/patent/US5349070A

## CPC

- C07D 309/40: Oxygen atoms attached in positions 3 and 4, e.g. maltol
- A61P 7/02: Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A61P 43/00: Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The present invention relates to a novel salicylic acid-maltol conjugates of the formula I. ##STR1## wherein R represents H, alkyl groups containing C.sub.1-5 carbon atoms or alkanoyl groups containing C.sub.1-5 carbon atoms. R.sub.1 represents H or alkyl groups containing C.sub.1-5 carbon atoms. A novel maltol esters of salicylic acid derivatives exhibit antioxidant and antithrombotic activities to a greater extent than salicylic acid derivatives.

## Claims

### Claim 1

A compound of the following formula I ##STR5## wherein R represents H, alkyl group containing C.sub.1-5 carbon atoms or alkanoyl group containing C.sub.1-5 carbon atoms, R.sub.1 represents H or alkyl group containing C.sub.1-5 carbon atoms.