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US 5,346,905 AGranted
1-substituted 1H-imidazo-[4,5-C]quinolin-4-amines
AssigneeMinnesota Mining and Manufacturing Company
InventorJohn F. Gerster
Life of this patent
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Abstract
1-substituted 1H-imidazo[4,5-c]quinolin-4-amines, active as immunomodulators and antiviral agents. Also, intermediates in the preparation of such compounds, pharmaceutical compositions, and pharmacological methods of use.
Claims11
A compound of the formula:
- ##STR11## wherein R'.sub.1 is hydrogen and R.sub.1 is 2-, 3-, or 4-pyridyl;
- R.sub.2 is selected from the group consisting of hydrogen, alkyl of one to about four carbon atoms, phenyl, and substituted phenyl wherein the substituent is selected from the group consisting of alkyl of one to about four carbon atoms, alkoxy of one to about four carbon atoms, and halogen;
- and
- R is selected from the group consisting of hydrogen, straight chain or branched chain alkoxy containing one to about four carbon atoms, halogen, and straight chain or branched chain alkyl containing one to about four carbon atoms;
- or a pharmaceutically acceptable acid addition salt thereof.
2 more elements
Dependencies are inferred from the claim text.