# US 5,346,698 A · Synergistic pesticidal compositions

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- Number: US 5,346,698 A
- Document ID: US5346698A
- Status: Granted
- Kind: A
- Application number: 08/028,041
- Filed: 1993-03-08
- Granted: 1994-09-13
- Earliest claimed: 1991-01-15
- Assignees: Mycogen Corporation
- Inventors: Kenneth D. Abercrombie
- Web page: https://patentgrep.com/patent/US5346698A

## CPC

- A01N 43/90: having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS

## Abstract

Described and claimed are methods and compositions for the control of pests. According to the subject invention, a fatty acid or mixture of fatty acids can be combined with one or more avermectins or related compounds to achieve synergistic control of pests.

## Claims

### Claim 1

A composition for the control of a pest, said composition comprising a first ingredient which is a monocarboxylic acid having about seven to about twenty carbon atoms, or a salt thereof, or a mixture of said monocarboxylic acids or salts thereof, and a second ingredient which is an avermectin, ivermectin, or milbemycin, wherein said first ingredient is present in a concentration of at least about 0.2% and the second ingredient is present in a concentration between about 3 ppm and about 110 ppm.

### Claim 2 (depends on 1)

The composition, according to claim 1, wherein said first ingredient can be represented by the following formula:
R.sub.1 Y.sub.1 Y.sub.2 COOR.sub.2
wherein
R.sub.1 =C6 to C19 saturated or unsaturated hydrocarbon, or an epoxide, or cyclopropane thereof
Y.sub.1 =H, C1-C5 hydrocarbon, or hydroxyl at any position along R.sub.1
Y.sub.2 =H, C1-C5 hydrocarbon, or hydroxyl at any position along R.sub.1
R.sub.2 =H, or salt.

### Claim 3 (depends on 1)

The composition, according to claim 1, wherein said first ingredient has from about fifteen to about twenty carbons.

### Claim 4 (depends on 1)

The composition, according to claim 1, wherein said first ingredient is a mixture of monocarboxylic acids or salts thereof.

### Claim 5 (depends on 1)

The composition, according to claim 1, wherein said first ingredient is saturated and unsubstituted.

### Claim 6 (depends on 1)

The composition, according to claim 1, wherein said first ingredient is oleic acid or a salt thereof.

### Claim 7 (depends on 1)

The composition, according to claim 1, wherein said second ingredient is an avermectin.

### Claim 8 (depends on 1)

The composition, according to claim 1, wherein said second ingredient is a milbemycin.

### Claim 9 (depends on 1)

The composition, according to claim 1, wherein said second ingredient is an ivermectin.

### Claim 10 (depends on 1)

The composition, according to claim 1, wherein said composition is formulated to be a drench product to be applied to livestock or pets.

### Claim 11 (depends on 10)

The composition, according to claim 10, wherein said first ingredient has from about seven to about eighteen carbons.

### Claim 12 (depends on 11)

The composition, according to claim 11, wherein said first ingredient is decanoic or nonanoic acid or salts thereof.

### Claim 13 (depends on 1)

The composition, according to claim 1, wherein said first ingredient is a metal salt of a monocarboxylic acid.

### Claim 14

A method for the control of a pest, said method comprising the administration to said pest of an effective amount of a composition comprising a first ingredient which is a monocarboxylic acid having about seven to about twenty carbons, or a salt thereof, or a mixture of monocarboxylic acids or salts thereof, and a second ingredient which is an avermectin, ivermectin, or milbemycin, wherein said first ingredient is applied at a rate of at least about 1 lb/acre, and said second ingredient is applied at a rate of about 0.0006 lbs/acre to about 0.02 lbs/acre.

### Claim 15 (depends on 14)

The method, according to claim 14, wherein said first ingredient can be represented by the following formula:
R.sub.1 Y.sub.1 Y.sub.2 COOR.sub.2
wherein
R.sub.1 =C6 to C19 saturated or unsaturated hydrocarbon, or an epoxide, or cyclopropane thereof
Y.sub.1 =H, C1-C5 hydrocarbon, or hydroxyl at any position along R.sub.1
Y.sub.2 =H, C1-C5 hydrocarbon, or hydroxyl at any position along R.sub.1
R.sub.2 =H, or salt.

### Claim 16 (depends on 14)

The method, according to claim 14, wherein said first ingredient has from about fifteen to about twenty carbons.

### Claim 17 (depends on 14)

The method, according to claim 14, wherein said first ingredient is oleic acid or a salt thereof.

### Claim 18 (depends on 14)

The method, according to claim 14, wherein said second ingredient is an avermectin.

### Claim 19 (depends on 14)

The method, according to claim 14, wherein said second ingredient is a milbemycin.

### Claim 20 (depends on 14)

The method, according to claim 14, wherein said second ingredient is ivermectin.

### Claim 21 (depends on 14)

The method, according to claim 14, wherein said composition is formulated to be a drench product to be applied to livestock or pets.

### Claim 22 (depends on 14)

The method, according to claim 14, wherein said first ingredient has from about seven to about eighteen carbons.

### Claim 23 (depends on 14)

The method, according to claim 14, wherein said first ingredient is a metal salt of a monocarboxylic acid.

### Claim 24 (depends on 14)

The method, according to claim 14, wherein said pest is in a taxonomic family selected from the group consisting of Tetranychidae, Eriophyidae, Tenuipalpidae, Tarsenomidae, Aleyrodidae, Psyllidae, Agromyzidae, Cicadellidae, Membracidae, Coccidae, Pseudococcidae, and Diaspididae.

### Claim 25 (depends on 14)

The method, according to claim 14, wherein said pest is selected from the group consisting of Thysanoptera, Hymenoptera, Hemiptera, Cicadellidae, Membracidae, Coccidae, Pseudococcidae, Diaspididae, and Solenopsis.

### Claim 26 (depends on 14)

The method, according to claim 14, wherein said pest is selected from the group consisting of mites and whiteflies.

### Claim 27 (depends on 21)

The method, according to claim 21, wherein said pest is selected from the group consisting of fleas, ticks, mites, lice, and flies.

### Claim 28

A method for the control of a pest, said method comprising the sequential application to said pest of a first composition comprising a monocarboxylic acid having about seven to about twenty carbon atoms, or a salt thereof, or a mixture of monocarboxylic acids or salts thereof, and a second composition comprising avermectin, ivermectin, or milbemycin wherein said first ingredient is present in a concentration of at least about 0.2% and the second ingredient is present in a concentration between about 3 ppm and about 110 ppm.

### Claim 29 (depends on 28)

The method, according to claim 28, wherein said monocarboxylic acid can be represented by the following formula:
R.sub.1 Y.sub.1 Y.sub.2 COOR.sub.2
wherein
R.sub.1 =C6 to C19 saturated or unsaturated hydrocarbon, or an epoxide, or cyclopropane thereof
Y.sub.1 =H, C1-C5 hydrocarbon, or hydroxyl at any position along R.sub.1
Y.sub.2 =H, C1-C5 hydrocarbon, or hydroxyl at any position along R.sub.1
R.sub.2 =H, or salt.

### Claim 30 (depends on 28)

The method, according to claim 28, wherein said monocarboxylic acid is oleic acid or a salt thereof.
