# US 5,346,688 A · Iodinated wetting agents

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- Number: US 5,346,688 A
- Document ID: US5346688A
- Status: Granted
- Kind: A
- Application number: 07/991,640
- Filed: 1992-12-16
- Granted: 1994-09-13
- Earliest claimed: 1992-12-16
- Assignees: Sterling Winthrop Inc.
- Inventors: Edward R. Bacon; Gregory L. McIntire
- Web page: https://patentgrep.com/patent/US5346688A

## CPC

- C07C 233/54: having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
- C07C: ACYCLIC OR CARBOCYCLIC COMPOUNDS

## Abstract

Compounds having the structure ##STR1## wherein (Z)--COO is the residue of an iodinated aromatic acid; M is H, a cation, --CH.sub.2 CH.sub.2 O--.sub.m H, and --CH.sub.2 CH(OH)O--.sub.p H; m is an integer from 1 to 150; p is an integer from 1 to 50; and L is one or more divalent linking groups selected from alkylene, cycloalkylene, arylene, arylenealkylene, and alkylenearylene are particularly useful as wetting agents in x-ray imaging compositions.

## Claims

### Claim 1

A compound having the structure ##STR4## wherein M is H or a cation.

### Claim 2

A compound having the structure ##STR5##

### Claim 3 (depends on 1)

An x-ray contrast composition comprising the compound of claim 1.

### Claim 4 (depends on 3)

The x-ray contrast composition of claim 3 further including a pharmaceutically acceptable carrier.

### Claim 5 (depends on 3)

A method of medical x-ray diagnostic imaging which comprises administering to the body of a mammal a contrast effective amount of the x-ray contrast composition of claim 3.