# US 5,346,481 A · Vaccine delivery system

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- Number: US 5,346,481 A
- Document ID: US5346481A
- Status: Granted
- Kind: A
- Application number: 08/137,239
- Filed: 1993-10-14
- Granted: 1994-09-13
- Earliest claimed: 1993-10-14
- Assignees: Merck & Co., Inc.
- Inventors: Leonid Bunin
- Web page: https://patentgrep.com/patent/US5346481A

## CPC

- A61M 5/282: {by compression of deformable ampoule or carpule wall}
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

A disposable vaccine delivery system containing a single dosage vaccine, having a compressible "hour-glass" shaped container portion filled with a needle, containing the vaccine, enclosed in a rigid clamp assembly having syringe-type activation means for compressing and expelling the vaccine contents into the human subject.

## Claims

### Claim 1

A vaccine delivery system suitable for human or animal administration comprising a single dosage hypodermic syringe having an "hour-glass" shaped container portion made of plastic, said container portion sized so that the air and the minor drop of contents ejected during aspiration is equivalent in volume to the lower half of the "hour-glass" shaped container; a needle portion comprising a hollow sharp needle extending from one neck of the plastic container portion and a rigid clamp assembly means fitted with plunger means at the other end which can be slidably moved over the container portion expel the container contents.

### Claim 2 (depends on 1)

The system of claim 1 in which the container portion is disposable and made of a thermoformed plastic compatible with medication.

### Claim 3 (depends on 2)

The system of claim 2 in which the container portion is made of PVC, polypropylene or PET/polyethylene laminate.

### Claim 4 (depends on 1)

The system of claim 1 in which the rigid clamp assembly is multiuse and made of a moldable plastic.

### Claim 5 (depends on 4)

The system of claim 4 which the clamp assembly is made of Delrin polyester.

### Claim 6 (depends on 5)

The system of claim 5 in which the clamp assembly has a flat surface to receive the container portion, fitted on one end with a snap collar to engage the neck of the container portion and having plunger means at the other end.