# US 5,345,174 A · Slice-selective polarization transfer for localized solid-state NMR spectroscopy

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- Number: US 5,345,174 A
- Document ID: US5345174A
- Status: Granted
- Kind: A
- Application number: 07/944,847
- Filed: 1992-09-14
- Granted: 1994-09-06
- Earliest claimed: 1991-09-14
- Assignees: Bruker Analytische Messtechnik GmbH
- Inventors: Rainer Kimmich; Dan Demco; Siegfried Hafner
- Web page: https://patentgrep.com/patent/US5345174A

## CPC

- G01R 33/4816: {NMR imaging of samples with ultrashort relaxation times such as solid samples, e.g. MRI using ultrashort TE [UTE], single point imaging, constant time imaging}
- G01R: MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES (indicating correct tuning of resonant circuits H03J3/12)

## Abstract

A new method of spatial localization in solids using the high off-resonance sensitivity of heteronuclear polarization transfer is presented in theory and experiment. Application in imaging and volume-selective spectroscopy are discussed and test experiments to this end are reported.

## Claims

### Claim 1

A method for volume-selective nuclear magnetic resonance (NMR) spectroscopy or NMR-imaging comprising the steps of,
a) locating a sample within a homogeneous static magnetic field B.sub.0, said sample containing a first and second nuclear species,
b) applying a magnetic field gradient to the sample and,
c) irradiating a contact-RF-Pulse into the sample within a time interval during which the magnetic field gradient is applied, whereby a spin order transfer (SOT) from the first to the second nuclear species located in a slice transverse to a gradient direction of the magnetic field gradient is effected.

### Claim 2 (depends on 1)

The method according to claim 1, wherein the magnetic field gradient is a gradient of the static magnetic field B.sub.0.

### Claim 3 (depends on 2)

The method according to claim 2, comprising the additional step of irradiating a spin-lock pulse into the sample within the time interval during which the magnetic field gradient is applied.

### Claim 4 (depends on 1)

The method according to claim 1, wherein the magnetic field gradient is a gradient of an RF-field irradiated into the sample by means of the RF-pulse.

### Claim 5 (depends on 4)

The method according to claim 4, comprising the additional step of irradiating a spin-lock pulse into the sample within a time interval during which the magnetic field gradient is applied.