# US 5,344,917 A · Process for producing regenerated collagen fiber

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- Number: US 5,344,917 A
- Document ID: US5344917A
- Status: Granted
- Kind: A
- Application number: 07/997,487
- Filed: 1992-12-28
- Granted: 1994-09-06
- Earliest claimed: 1991-12-26
- Assignees: Kanegafuchi Kagaku Kogyo Kabushiki Kaisha
- Inventors: Mitsuru Furukawa; Masahiko Takada; Shoichi Murata; Atsushi Sasayama
- Web page: https://patentgrep.com/patent/US5344917A

## CPC

- D01F 4/00: Monocomponent artificial filaments or the like of proteins; Manufacture thereof
- D01F: CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS

## Abstract

A process for producing regenerated collagen fiber from solubilized collagen including adjusting a degree of swelling of solubilized collagen to 100 to 300% and then treating the resulting solubilized collagen with an aqueous solution of a metallic salt. The regenerated collagen fiber has excellent water resistance and undergoes no waving on contact with water.

## Claims

### Claim 1

A process for producing regenerated collagen fiber from solubilized collagen comprising adjusting a degree of swelling of solubilized collagen to 100 to 300% and then crosslinking the resulting solubilized collagen with an aqueous solution of a metallic salt.

### Claim 2 (depends on 1)

A process as claimed in claim 1, wherein said degree of swelling is adjusted by first drying solubilized collagen to produce a dried collagen having a maximum water content of 30% and then treating said dried collagen with a water-soluble organic crosslinking agent.

### Claim 3 (depends on 2)

A process as claimed in claim 2, wherein said water-soluble organic crosslinking agent is used as a 0.05 to 10% by weight aqueous solution at a pH of from 7 to 13.

### Claim 4 (depends on 2)

A process as claimed in claim 2, wherein said water-soluble organic crosslinking agent is used in combination with an inorganic salt.

### Claim 5 (depends on 1)

A process as claimed in claim 1, wherein said degree of swelling is adjusted by treating said solubilized collagen with a water-soluble organic solvent.