# US 5,344,650 A · Aqueous cosmetic composition and preparation method thereof > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 5,344,650 A - Document ID: US5344650A - Status: Granted - Kind: A - Application number: 08/022,394 - Filed: 1993-02-24 - Granted: 1994-09-06 - Earliest claimed: 1990-08-31 - Assignees: Kao Corporation - Inventors: Noriko Otsuka; Ichiro Tokimitsu - Web page: https://patentgrep.com/patent/US5344650A ## CPC - A61K 8/68: Sphingolipids, e.g. ceramides, cerebrosides, gangliosides - A61K 8/06: Emulsions - A61K 8/062: {Oil-in-water emulsions} - A61K 8/63: Steroids; Derivatives thereof - A61Q 19/00: Preparations for care of the skin - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS ## Abstract An emulsion-type aqueous cosmetic composition comprising: (i) a mixture of oil and fat, wherein said fat is present in at least 70 wt. % of said mixture, and at least 50 wt. % of said fat is at least one lipid selected from the group consisting of higher fatty acids, cholesterol, cholesterol fatty acid esters, ceramides, sugar ceramides, and compounds having the following formula (I): ##STR1## wherein R.sup.1 is a linear or branched, saturated or unsaturated hydrocarbon group having 10 to 26 carbon atoms, and R.sup.2 is a linear or branched, saturated or unsaturated hydrocarbon group having 9 to 25 carbon atoms, (ii) an aqueous medium, and (iii) an emulsifying agent, said mixture of oil and fat being dispersed in said aqueous medium with said emulsifying agent. ## Claims ### Claim 1 An oil-in-water cosmetic composition, prepared by: (A) heating a mixture comprising (i) an oil selected from the group consisting of liquid paraffin, mineral oil, squalane, petroleum jelly, lower alcohol esters of fatty acids, jojoba oil, whale oil, glycerides of fatty acids, liquid acetate esters of fatty alcohols, aloe, vitamins, and mixtures thereof; (ii) a fat selected from the group consisting of higher fatty acids, cholesterol, cholesterol fatty acid esters, ceramides and compounds having the following formula (I): ##STR8## wherein R.sup.1 is a linear or branched, saturated or unsaturated hydrocarbon group having 10 to 26 carbon atoms, and R.sup.2 is a linear or branched, saturated or unsaturated hydrocarbon group having 9 to 25 carbon atoms, and mixtures thereof, said fat being present in at least 70 wt. % of the total of said oil and said fat; (iii) an emulsifying agent and (iv) a portion of from 0.1 to 5% of an aqueous medium selected from the group consisting of water and a combination of water and a water-soluble monohydric alcohol, at a temperature of from 60.degree. C. to 80.degree. C. for a length of time sufficient to provide a uniform solution; and (B) emulsifying said uniform solution with the balance of said aqueous medium. ### Claim 2 (depends on 1) An oil-in-water cosmetic composition according to claim 1, wherein said oil is a liquid at 25.degree. C., and said fat is solid at 25.degree. C. ### Claim 3 (depends on 1) An oil-in-water cosmetic composition according to claim 1, wherein fat further comprises at least one member selected from the group consisting of hydrocarbons, wax esters, glycerides of fatty acids and higher alcohols. ### Claim 4 (depends on 1) An oil-in-water cosmetic composition according to claim 1, wherein the amount of said mixture of oil and fat is from 0.5 to 20 wt. % of the total weight of said cosmetic composition. ### Claim 5 (depends on 1) An oil-in-water cosmetic composition according to claim 1, wherein the amount of said lipid is form 2 to 20 wt. % of the total weight of said cosmetic composition. ### Claim 6 (depends on 1) An oil-in-water cosmetic composition according to claim 1, wherein said emulsifying agent is a surface active agent of a polyoxyethylene alkyl ether phosphoric acid type having the following formula: ##STR9## wherein R is a hydrocarbon group of from 8 to 36 carbon atoms, n is a number of 1 to 10 on the average, and X is an inorganic or organic cation. ### Claim 7 (depends on 6) An oil-in-water cosmetic composition according to claim 6, wherein X is an inorganic cation. ### Claim 8 (depends on 1) A method for the preparation of an oil-in-water cosmetic composition set forth in claim 1, wherein said oil and said fat are a mixture, said fat being present in at least 70 wt. % of said mixture, and at least 50 wt. % of said fat is at least one lipid. ### Claim 9 (depends on 1) The composition of claim 1, wherein said ceramide is a sugar ceramide. ### Claim 10 A method for the preparation of an oil-in-water cosmetic composition, comprising the steps of: (a) mixing an oil, a fat, an emulsifying agent and a portion of an aqueous medium at a temperature of from 60.degree. C. to 80.degree. C., for a length of time sufficient to provide a uniform solution, said portion of said aqueous medium being from 0.1 to 5 wt. % of the amount of said aqueous medium to be included in said cosmetic composition; and (b) emulsifying said uniform solution with the balance of said aqueous medium. ### Claim 11 (depends on 1) The oil-in-water cosmetic composition of claim 1, wherein said mixture further comprises (v) from 0.5 to 10% by weight of the composition of a water-soluble polyhydric alcohol. ### Claim 12 (depends on 1) The oil-in-water cosmetic composition of claim 1, wherein said aqueous medium is water, and said aqueous medium further comprises a water-soluble polyhydric alcohol.