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US 5,342,752 AGranted
Method of inactivation of viral blood contaminants using acridine deriatives
AssigneeCryopharm Corporation
InventorsMatthew S. Platz, Raymond P. Goodrich, Jr., Victoria A. Wong
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Abstract
A method is provided for inactivating viral and/or bacterial and/or parasitic contamination in cellular blood matter or blood plasma protein fractions, using radiation sensitizing chemical compounds and irradiation with, for example, UV radiation.
Claims7
A method of reducing parasitic contamination in blood matter comprising red blood cells, platelets, blood plasma protein fractions or mixtures thereof comprising the steps of:
- (a) contacting said blood matter in vitro with a chemical sensitizer of the formulas:
- ##STR2## (b) exposing said blood matter and chemical sensitizer to radiation of sufficient energy and wavelength for a period of time sufficient to cause said sensitizer to substantially inactivate the parasitic contamination in said blood matter.
Dependencies are inferred from the claim text.