Thimerosal inactivated mycoplasma hyopneumoniae vaccine
AssigneeAmbico Inc.
InventorsGerald R. Fitzgerald, C. Joseph Welter
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Abstract
The invention relates to a method for making an inactivated vaccine of Mycoplasma hyopneumoniae by inactivating the bacteria with Thimerosal. The resulting bacterin is mixed with an adjuvant of aluminum hydroxide and DEAE dextran and injected into pigs. The resulting bacterin and adjuvant mixture can also be mixed with other bacteria such as Borderella and Pasteurella, for further adjuvant effect. Protective immunity against mycoplasmal pneumonia is elicited in swine using these vaccines.
Claims12
A method for producing a Mycoplasma hyopneumonia vaccine comprising contacting live Mycoplasma hyopneumonia bacteria with an inactivating concentration of Thimerosal to inactivate the Mycoplasma hyopneumonia bacteria, and incorporating the inactivated bacteria into a pharmaceutically acceptable carrier to produce a Mycoplasma hyopneumonia vaccine.
Dependencies are inferred from the claim text.