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US 5,338,448 AGranted
Method of preventing contamination of a chromatography column
AssigneeSarasep, Inc.
InventorDouglas T. Gjerde
Life of this patent
Estimating the term…
Abstract
Liquid chromatography separation columns can be protected from contamination with particulate and dissolved contaminants by the use of a thin protective pad which removes contaminants from a sample stream prior to separation of the sample on the separation column. The protective pad may be in the form of a guard disk positioned inline or directly contacting the separation column.
Claims22
A method of preventing contamination of a chromatography separation column containing stationary phase chromatographic material, by particulate or dissolved contaminants in a sample stream, comprising:
- retaining particulate and dissolved contaminants in a protective pad by passing the sample stream through the protective pad before the sample stream contacts the separation column, wherein said protective pad comprises a fabric or membrane sorptive chromatographic material.
Dependencies are inferred from the claim text.