Oral collection device and method for immunoassay
AssigneeEpitope, Inc.
InventorsAndrew S. Goldstein, Stefan Gavojdea, David F. Zogg
Life of this patent
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Abstract
A method and device for collecting immunoglobulins and other analytes from the oral cavity for immunological and other testing. The device is a treated absorbent pad used to collect a specimen having a high concentration of immunoglobulins or other analytes. The specimen can be subjected to a basic immunological testing technique which can be used as a tool for screening a patient for diseases. A test kit is also provided.
Claims28
A method of preferentially collecting mucosal transudate from an oral cavity for testing comprising the steps of:
- (a) inserting an absorbent pad into the oral cavity,
- (b) contacting the pad with the oral mucosa without masticating said pad,
- (c) removing the pad from the oral cavity, and
- (d) preserving the pad for subsequent removal of the collected mucosal transudate from the pad for testing.
A method for recovering mucosal transudate which has been preferentially collected in an absorbent pad for testing, wherein the pad is stored in a container after removal from the oral cavity, wherein said container comprises an open upper end sealed with a removable stopper and a lower end having an opening communicating the interior of the container with the outside, said opening having a removable seal thereon during storage of said pad, said method comprising providing a preservative solution in said container prior to storing said pad within said container, eluting said mucosal transudate with a solvent or diluent therefor within said container, removing said seal, placing said container in a centrifuge tube with the lower end of said container within the centrifuge tube to form an assembly, and centrifuging said assembly to thereby draw said solvent or diluent containing said mucosal transudate into said centrifuge tube.
A kit for preferentially collecting and storing mucosa preferentially transudate for subsequent testing comprising a pad and a container for storing the pad;
- said container containing a preservative solution and comprising an open upper end adapted to be sealed with a removable stopper and a lower end having an opening communicating the interior of the container with the outside, said opening being selectively sealed during storage of said mucosal transudate and unsealed for removal of said collected mucosal transudate for subsequent testing.
Dependencies are inferred from the claim text.