Process for producing polyesters by fermentation: a process for producing optically active carboxylic acids and esters: articles of manufacture comprising polyester
AssigneeRijksuniversiteit te Groningen
InventorsBernard Witholt, Roland G. Lageveen
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Abstract
This invention relates to a process for producing polyester biopolymers by culturing Pseudomonas oleovorans bacteria on substrates comprising certain nutrients. The nature of the polyesters can be varied by varying the nature of the carbon source used. In this way polyesters with unsaturated double bonds can be produced, too. From the polyesters, optically active carboxylic acids or esters are produced. The polymers can be used for making articles of manufacture, such as sutures, films, skin and bone grafts.
Claims6
An optically active polyester compound isolated from Pseudomonas oleovorans cells cultured in a nutrient medium in the presence of a carbon source and at least one nutrient essential for growth, said carbon source comprising at least one paraffin product containing 6-7 or 9-12 carbon atoms or at least one paraffin oxidation product containing 6-12 carbon atoms, said polyester compound comprising units other than exclusively 3-hydroxyoctanoate units or 3-hydroxyoctanoate and 3-hydroxyhectanoate units having the structural formula:
- ##STR4## wherein m represents an integer of 2-8.
An optically active polyester compound isolated from Pseudomonas oleovorans cells cultured in a nutrient medium in the presence of a carbon source and at least one nutrient essential for growth, said carbon source comprising at least one compound selected from unbranched 1-olefins containing 7-12 carbon atoms and optionally one or more non-branched paraffins or paraffin oxidation products containing 6-12 carbon atoms, said polyester compound comprising units having the structural formula (1):
- ##STR5## and units having the structural formula (2):
- ##STR6## wherein m represents an integer of 2-8.
Dependencies are inferred from the claim text.