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US 5,334,611 AGranted
6-ethyl mitomycin derivatives
AssigneeKyowa Hakko Kogyo Co., Ltd.
InventorsHitoshi Arai, Yutaka Kanda, Motomichi Kono, Masaji Kasai, Tadashi Ashizawa, Katsushige Gomi
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Abstract
Novel mitomycin derivatives represented by the formula (I) are obtained by introducing a substituent at the 6-position. The mitomycin derivatives of the present invention have an antitumor activity.
Claims2
A mitomycin derivative represented by the formula:
- ##STR19## wherein Y and Z represent independently methyl or hydrogen;
- one of R.sup.1 and R.sup.2 represents CH.sub.2 OCONH.sub.2 and the other represents hydrogen.
Dependencies are inferred from the claim text.