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US 5,334,610 AGranted
.alpha.-aryl-.alpha.-hydroxy-.beta.-imidazolinyl-propionamides
AssigneeBayer Aktiengesellschaft
InventorsWilfried Draber, Hilmar Bischoff
Life of this patent
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Abstract
The present invention relates to novel .alpha.-aryl-.alpha.-hydroxy-.beta.-imidazolinyl-propionamides of the general formula (I) ##STR1## in which n, R.sup.1 to R.sup.4 and X have the meaning indicated in the description, to a process for their preparation and to their use in medicaments.
Claims5
A compound of the formula ##STR9## in which n is a number from 0 to 5,
- R.sup.1 and R.sup.2 each independently is hydrogen or C.sub.1 -C.sub.6 -alkyl or together are C.sub.4 -C.sub.6 -alkanediyl,
- R.sup.3 is hydrogen or C.sub.1 -C.sub.6 -alkyl,
- R.sup.4 represents hydrogen;
- C.sub.1-6 -alkyl optionally substituted by fluorine, chlorine, or C.sub.1-4 -alkoxy;
- C.sub.3-7 -cycloalkyl or C.sub.3-7 -cycloalkyl-C.sub.1-4 -alkyl each optionally substituted by fluorine, chlorine, bromine or C.sub.1-4 alkyl;
- phenyl, naphthyl, phenyl-C.sub.1-4 -alkyl or naphthyl-C.sub.1-4 -alkyl each optionally substituted by fluorine, chlorine, bromine, cyano or nitro or by C.sub.1-4 alkyl, C.sub.1-4 -alkoxy, C.sub.1-4 -alkylthio, C.sub.1-4 -alkylsulphinyl or C.sub.1-4 -alkylsulphonyl each optionally substituted by fluorine and/or chlorine;
- X represents halogen, or C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkoxy each of which is optionally substituted by fluorine and/or chlorine,
- or a physiologically tolerated acid adduct thereof.
5 more elements
Dependencies are inferred from the claim text.