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US 5,334,532 AGranted
PDGF-B fusion protein, vectors, and host cells for use in production thereof
AssigneeImClone Systems Incorporated
InventorsCharles Tackney, Jurgen Hoppe, Wolfram Eichner, Herbert Weich
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Abstract
The present invention provides a method for production of recombinant PDGF-B in prokaryotic cells. Also provided are DNA constructs for fusion protein useful in the production of the biologically active product.
Claims3
An expression vector for producing PDGF-B comprising a DNA molecule having the nucleotide sequence of FIG. 3.
The E. coli host cell transformed with plasmid pE-pF14 which is deposited with the ATCC under accession number 68104.
A PDGF-B fusion protein comprising the amino acid sequence of FIG. 3.
Dependencies are inferred from the claim text.