Process for producing riboflavin by fermentation

Abstract

The present invention provides a process for producing riboflavin by fermentation, a method for providing microorganisms having an improved riboflavin-producing capability, and strains of microorganisms having improved riboflavin-producing ability. The strains of the present invention belong to the genus Bacillus, have reduced activity of hydrolysing phosphoric acid from 5'-guanylic acid, and have the ability of producing riboflavin. Mutants used in the processes of this invention have an improved ability of producing riboflavin and are capable of producing or accumulating a large amount of riboflavin in the culture medium. The processes of this invention are therefore suitable for producing riboflavin in an effective manner at a low cost.

Dependencies are inferred from the claim text.