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US 5,332,835 AGranted
Process for fluorinating 1-phenyl-2-amino-1,3-propanediol compounds and new oxazoline compounds useful in this process
AssigneeZambon S.p.A.
InventorsGiancarlo Jommi, Dario Chiarino, Roberto Pagliarin
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Abstract
Replacement with fluorine of the primary hydroxy group of 1-phenyl-2-amino-1,3-propanediol compounds wherein the secundary hydroxy group and the amino group have been suitably protected. The reaction is carried out with an inorganic fluoride in a polyglycol. New oxazoline compounds particularly useful in said-process.
Claims1
A compound of the formula ##STR16## wherein R is CH.sub.3 S--, CH.sub.3 SO--, or CH.sub.3 SO.sub.2 --;
- X1 is phenyl;
- and Y is OH.
Dependencies are inferred from the claim text.