Benzofuran derivatives
AssigneeGlaxo Group Limited
InventorsMichael D. Dowle, Duncan B. Judd
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Abstract
The invention provides compounds of formula (I): ##STR1## or a physiologically acceptable salt, solvate or metabolically labile ester thereof wherein Ar represents the group ##STR2## wherein R.sup.3 represents an acidic group selected from --CO.sub.2 H, --NHSO.sub.2 CF.sub.3 or a C-linked tetrazolyl group; Het represents the group ##STR3## with all other undefined groups being defined in the specification. The compounds may be used in the treatment or prophylaxis of hypertension and diseases associated with cognitive disorders.
Claims19
The compound 1-[[3-bromo-2-[2-[[(trifluoromethyl)sulphonyl]amino]phenyl]-5-benzofuranyl ]methyl]-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxamide, or a physiologically acceptable salt or solvate thereof.
1-[[3-bromo-2-[2-[[(trifluoromethyl)sulphonyl]amino]phenyl]-5-benz ofuranyl]methyl]-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxamide.
Dependencies are inferred from the claim text.