1,2-dihydro-2-oxopyridines

A 1,2-dihydro-2-oxopyridine compound of formula I ##STR10## wherein R is the radical ##STR11## R.sup.1 is H, Hal, A, OA or NO.sub.2 ;

• R.sup.2 is COOH, COOA, CN, NO.sub.2, NH.sub.2, NHCOR.sup.7, NHSO.sub.2 R.sup.7 or tetrazol-5-yl;
• R.sup.3 is CH.sub.2 NR.sup.10 R.sup.11, or tetrazol-5-yl;
• R.sup.4 is H or A;
• R.sup.5, R.sup.6 and R.sup.10 are in each case independently H, A, alkenyl having 2-6 C atoms, alkynyl having 2-6 C atoms, Ar or Ar-alkyl having 1-6 C atoms in the alkyl moiety;
• R.sup.7 is A or A monosubstituted or polysubstituted by F;
• R.sup.11 is H, A, A monosubstituted or polysubstituted by F, Ar, Ar-alkyl having 1-6 C atoms in the alkyl moiety, CO-A, CO-Ar, CO-alkyl-Ar having 1-6 C atoms in the alkyl moiety, COOA, COOAr, COO--alkyl--Ar having 1-6 C atoms in the alkyl moiety, CONR.sup.12 R.sup.13, SO.sub.2 R.sup.7 or SO.sub.2 Ar,
• NR.sup.10 R.sup.11 can also be pyrrolidino, piperidino, morpholino, succinimido or phthalimido;
• R.sup.12 and R.sup.13 are in each case independently H, A, cycloalkyl having 3-8 C atoms, alkenyl having 2-6 C atoms, alkynyl having 2-6 C atoms, or Ar;
• X is absent or is --CO--, --O--, --NH--CO--, --CO--NH--, --CH.sub.2 --O-- or --O--CH.sub.2 --;
• A is alkyl having 1-6 C atoms;
• Ar is phenyl which is unsubstituted or monosubstituted by A, OA, CF.sub.3, Hal or NO.sub.2 ;
• and
• Hal is F, Cl, Br or I;
• or
• a physiologically acceptable salt.