Substituted derivatives of 20,21-dinoreburnamenine, their preparation process and the new intermediates thus obtained, their use as medicaments and the pharmaceutical compositions containing them
AssigneeRoussel Uclaf
InventorsNurgun Aktogu, Francois Clemence, Claude Oberlander
Life of this patent
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Abstract
A compound and all possible racemic or optically active isomer forms, selected from the group consisting of compound of the formula ##STR1## wherein the substituents are defined as set forth in the application as filed. Useful for treating cerebral insufficiencies of anoxic or ischemic origin.
Claims12
A compound in all possible racemic or optically active isomer forms selected from the group consisting of a compound of the formula ##STR66## and R.sub.1, R.sub.2 and R.sub.3 are individually selected from the group consisting of hydrogen, halogen, alkyl of 1 to 5 carbons atoms, alkoxy of 1 to 5 carbon atoms, --OH, --CF.sub.3, --NO.sub.2, --NH.sub.2, mono- and dialkylamino of 1 to 5 carbon atoms and acyl of an aliphatic carboxylic acid of 1 to 6 carbon atoms with the proviso that at least two are other than hydrogen and their non-toxic, pharmaceutically acceptable acid addition salts.
Dependencies are inferred from the claim text.