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US 5,332,738 AGranted
Imidazolidine antipsychotic agents
AssigneeNcNeilab, Inc.
InventorsMalcolm K. Scott, Allen B. Reitz
Life of this patent
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Abstract
Compounds of the general formula I ##STR1## are disclosed as novel antipsychotic agents. Pharmaceutical compositions and methods of treating convulsions employing such compounds of formula I.
Claims16
A compound represented by ##STR6## where A is N;
- Ar is aryl or substituted aryl;
- wherein the substituents for the aryl are selected from any of C.sub.1 -C.sub.8 alkyl, C.sub.3 -C.sub.10 cycloalkyl, C.sub.1 -C.sub.8 hydroxyalkyl, C.sub.1 -C.sub.8 alkoxy, aryloxy, hydroxyl, trifluoromethyl, trifluoromethoxy, cyano, C.sub.1 -C.sub.8 alkythio, halogen nitro, C.sub.1 -C.sub.8 haloalkyl, amino or C.sub.1 -C.sub.8 mono- or di- alkylamino;
- R.sub.1 and R.sub.2 may be the same or different and are selected from either .dbd.O (oxo group) or .dbd.S (thioxo group);
- or the pharmaceutically acceptable salts thereof.
1 more element
Dependencies are inferred from the claim text.