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US 5,331,096 AGranted
2- and 3-sulfur derivatives of 1,5-iminosugars
AssigneeG. D. Searle & Co.
InventorsFrancis J. Koszyk, Richard A. Mueller
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Abstract
Novel derivatives of 1-deoxynojirimycin are disclosed which have thio or sulfinyl substituents at C-2 or C-3. These compounds are useful inhibitors of lentiviruses such as visna virus and human immunodeficiency virus. Methods of chemical synthesis of these derivatives and intermediates therefor are also disclosed.
Claims4
A compound of the formula ##STR31## wherein R .dbd. C.sub.1 -C.sub.4 alkyl or phenyl R' .dbd. H or COOCH.sub.2 CH.sub.2 OCH.sub.3.
Dependencies are inferred from the claim text.