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US 5,331,090 AGranted
CR2 ligand compositions and methods for modulating immune cell functions
AssigneeCalifornia Institute of Biological Research
InventorWaldemar Lernhardt
Life of this patent
Estimating the term…
Abstract
Synthetic polypeptides corresponding to the B lymphocyte CR2 receptor binding site present on a CR2 ligand are disclosed together with polypeptide aggregates, compositions, anti-polypeptide antibodies and methods of preparing and using the polypeptides and antibodies.
Claims2
A CR2 ligand consisting essentially of a polypeptide having an amino acid residue sequence selected from the group consisting of
- ______________________________________ NSGVEA, QNSGVEALI, TQNSGVEALI, VTQNSGVEALI, LVTQNSGVEALI, QNSGVEALIHAIL, QNSGVEALIHAI, QNSGVEALIH, PAIVEAG, KPAIVEAG, NKPAIVEAG, SNKPAIVEAG, PAIVEAGG, PAIVEAGGM, and PAIVEAGGMQ, ______________________________________
- said ligand having the ability to specifically bind CR2 receptor.
A CR2 ligand consisting essentially of a polypeptide having an amino acid residue sequence selected form the group consisting of:
- ______________________________________ QSNGVEALT, QNSGLEALT, QNSGLEALI, QSNGVEALI, QNSVGEALI, QPAIVEAG, QNAIVEAG, QPAIVEAL, QPAIVEALI, QPAIVEALT, QPAILEAG, QPAILEAGT, QPAIVEAGI, QNAIVEALI, and QNAIVEALT, ______________________________________
- said ligand having the ability to specifically bind CR2 receptor.
Dependencies are inferred from the claim text.