Pharmaceutical compositions for treating adrenoleukodystrophy
AssigneeCroda International PLC
InventorsDonald Suddaby, Keith Coupland
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Abstract
A composition for the treatment of adrenoleukodystrophy comprises a mixture of erucic acid and less than 20% of C20:1, in the absence of any C24:0 and C26:0 acids (all the acids being as such or in the form of physiologically acceptable derivatives, e.g. the triglycerides). For dietary administration, the compositions are preferably mixed with a dietary supplement comprising glyeceryl trioleate.
Claims10
A method for treating adrenoleukodystrophy, which comprises administering a pharmacologically effective amount of a composition which includes an effective amount of C22:1 long-chain fatty acid and no more than about 20 percent of C20:1 long-chain fatty acid, the ratios of said C22:1 to C20:1 acids being substantially greater than 2:1, said composition being substantially free of saturated fatty acids having 24 and 26 carbon atoms.
Dependencies are inferred from the claim text.