Arylalkyl esters of 4,5-dihydroxy-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic acid having therapeutical activity
AssigneeIstituto Gentili S.p.A.
InventorsSergio Rosini, Maurizio Mian
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Abstract
This application describes 3-arylalkyl esters of 4,5-dihydro-9,10-dioxo-2-anthracenecarboxylic acid and a process for making them. Also described is a method of using the compounds in the treatment of arthritis.
Claims11
A compound of formula (1) ##STR3## wherein R--CH.sub.2 --O-- is the residue of an R--CH.sub.2 OH alcohol derived from the reduction of an R--COOH carboxylic acid having anti-inflammatory action, which is a member selected from the group consisting of salicylic, arylacetic, arylpropionic, and anthranilic acids;
- or enantiomers, diastereoisomers and mixtures thereof or pharmaceutically acceptable salts thereof.
The method of treatment of a living subject affected by arthritis which consists of administering to said subject an effective amount of a composition containing as the active ingredient a compound of formula (1) ##STR4## wherein R--CH.sub.2 --O-- is the residue of an R--CH.sub.2 OH alcohol derived from the reduction of an R--COOH carboxylic acid having anti-inflammatory action, which is a member selected from the group consisting of salicylic, arylacetic, arylpropionic, and anthranilic acids;
- or enantiomers, diastereoisomers and mixtures thereof or pharmaceutically acceptable salts thereof.
Dependencies are inferred from the claim text.