Antimycotic compositions of nikkomycin compounds and azole antimycotics
AssigneeMiles Inc.
InventorsRichard F. Hector, Klaus Schaller, Heinrich F. Moeschler, Manfred Plempel
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Abstract
Nikkomycin compounds have been found to be orally or parenterally effective as anti-fungals in animals. They may be used alone or, preferably, in combination with azole antimycotics for a synergistic anti-fungal effect.
Claims2
A synergistically, fungicidally effective antimycotic composition comprising fungicidally effective amount of nikkomycin X or nikkomycin Z, and miconazole the weight of the nikkomycin X or Z to miconazole ranging from about 1:1 to about 30:1.
The method of treating animals infected with fungi, the method comprising administering to the animal a composition comprising synergistically effective amounts of nikkomycin X or nikkomycin Z and miconazole the weight ratio of the nikkomycin X or nikkomycin Z to miconazole ranging from about 1:1 to 30:1 and the amount of the composition administered to the animal ranging from 1 mg/kg to 1000 mg/kg of animal body weight per day.
Dependencies are inferred from the claim text.