Lipopeptide derivatives

A compound having the formula ##STR24## wherein U, V and W are independently H or OH, selected from those in which (1) U, V and W are all OH;

• (2) U and W are H and V is OH;
• (3) U and V are H and W is OH;
• R' is C.sub.5 -C.sub.23 alkyl, C.sub.5 -C.sub.23 alkenyl, C.sub.5 -C.sub.23 alkynyl or aryl;
• and
• R is
• (1) PO.sub.3 AH wherein A is H, C.sub.1 -C.sub.6 alkyl, phenyl or substituted phenyl wherein the substituent may be alkyl, alkyloxy, alkylthio, or alkylamino or a Li, Na, K, Mg and Ca cation salt thereof;
• (2) SO.sub.3 H or cation salt thereof as defined in (1)
• (3) COC.sub.n H.sub.2n CO.sub.2 H wherein n is 1 to 6 or a cation salt thereof as defined in (1)
• (4) CONAC.sub.n H.sub.2n CO.sub.2 H wherein A is as defined in (1), n is 1 to 6, or a cation salt thereof as defined in (1)
• (5) COOC.sub.n H.sub.2n CO.sub.2 H wherein n is 1 to 6, or a cation salt thereof as defined in (1)
• (6) CONA(CHB)CO.sub.2 H wherein B is a residue of an amino acid, or a cation salt thereof;
• as defined in (1)
• (7) COCHBNR.sub.1 R.sub.2 wherein B is a residue of an amino acid, R.sub.1 and R.sub.2 independently are H, C.sub.1 -C.sub.6 alkyl, and phenyl, and acid addition salts thereof;
• (8) CONAC.sub.n H.sub.2n NR.sub.1 R.sub.2 wherein A is as defined in (1), R.sub.1 and R.sub.2 independently are as defined in (7), n is 2 to 6, and acid addition salts thereof;
• (9) COOC.sub.n H.sub.2n NR.sub.1 R.sub.2 wherein R.sub.1 and R.sub.2 independently are as defined in (7), n is 2 to 6, and acid addition salts thereof;
• and
• (10) COC.sub.n H.sub.2n NR.sub.1 R.sub.2 wherein R.sub.1 and R.sub.2 independently are as defined in (7), n is 1 to 6 and acid addition salts thereof.