Enteric coated soft capsules and method of preparation thereof
AssigneeSterling Winthrop Inc.
InventorsShrikant N. Pagay, Gregg Stetsko
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Abstract
Soft capsules coated with an enteric coating comprising a 1:1 copolymer of methacrylic acid and methyl or ethyl acrylate or methyl or ethyl methacrylate and a plasticizer without need for a subcoating and optionally additionally coated with a protective coating comprising hydroxypropyl methylcellulose or hydroxypropyl cellulose or a mixture thereof and a plasticizer and method of preparation thereof are disclosed.
Claims7
A filled soft capsule not having a subcoating and coated with from about 1 to about 20 mg./cm..sup.2 of an enteric coating consisting essentially of by weight from about 60% to about 90% of a 1:1 copolymer of methacrylic acid and methyl or ethyl acrylate or methyl or ethyl methacrylate and from about 10% to about 40% of a plasticizer selected from the group consisting of triacetin, a polyethylene glycol having a molecular weight in the range from 400 to 3350, propylene glycol, dibutyl phthalate and triethyl citrate and a mixture thereof.
Dependencies are inferred from the claim text.