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US 5,329,029 AGranted
Phosphatidylalkanolamine derivatives and their use in generating phospholipid conjugates
OwnerBarbara Y. Waninventor
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Abstract
An efficient, technically straightforward and inexpensive process for generating conjugates of phospholipids with biologically important molecules is described.
Claims3
An N-substituted phosphatidylalkanolamine of the general formula:
- ##STR4## wherein R.sub.1, R.sub.2 independently represent alkyl, alkenyl, alkynyl, aryl, arylalkyl, or C(O)R.sub.3, wherein R.sub.3 represents alkyl, alkenyl, alkynyl, aryl, or arylalkyl;
- R.sub.4 represents H, alkyl or aryl;
- R.sub.5, R.sub.6 independently represent H, or alkyl;
- R.sub.7, R.sub.8 independently represent H, or alkyl;
- X represents alkyl, alkenyl or arylalkyl;
- and
- Y represents a cationic moiety including H.sup.+, alkali earth metal ions or ammonium ions.
4 more elements
An N-substituted phosphatidylalkanolamine of the general formula:
- ##STR5## wherein R.sub.1 and R.sub.2 independently comprise a fatty acid residue,
- R.sub.4 comprises H, alkyl or aryl
- R.sub.5, R.sub.6, R.sub.7 and R.sub.8 independently comprise H or an alkyl,
- X comprises alkyl, alkenyl or arylalkyl;
- and
- Y comprises H.sup.+.
3 more elements
Dependencies are inferred from the claim text.