Metal complexes of polyethylene glycol carbamate derivatives of desferrioxamine B
AssigneeCiba-Geigy Corporation
InventorsHeinrich Peter, Theophile Moerker
Life of this patent
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Abstract
Compounds of the formula ##STR1## in which R is alkyl having up to 4 carbon atoms, n has an average value of at least 9, X is a radical of the formula --C(.dbd.O)--(NH--SO.sub.2).sub.m -- in which m is 0 or 1 and, if m is 1, the carhonyl group may be bonded to the oxygen atom or to the nitrogen atom, and each of the radicals A.sub.1, A.sub.2 and A.sub.3, independently of the others, is hydrogen or an acyl radical, and salts of salt-forming compounds of formula I, as well as metal complexes of compounds of formula I, in which A.sub.1, A.sub.2 and A.sub.3 are hydrogen can be used as metal chelators and as auxiliaries in diagnosis.
Claims6
A complex of a metal ion and a compound of the formula ##STR7## in which R is alkyl having up to 4 carbon atoms, n has an average value of at least 9, X is a radical of the formula --C(.dbd.O)--(NH--SO.sub.2).sub.m -- in which m is 0 or 1, and, if m is 1, the carbonyl group may be bonded to the oxygen atom or to the nitrogen atom, wherein the metal ion is selected from the group consisting of paramagnetic transition metals and metals of main group 3 of the Periodic Table.
Dependencies are inferred from the claim text.