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US 5,328,987 AGranted
IgA Fc receptors
AssigneeImmunex Corporation
InventorCharles R. Maliszewski
Life of this patent
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Abstract
The present invention provides an isolated DNA sequence encoding soluble and membrane bound forms of a mammalian IgA Fc receptor, as well as recombinant expression vectors and host cells suitable for expressing the protein.
Claims5
An isolated, substantially homogeneous, biologically active mammalian IgA Fc receptor, wherein the receptor is encoded by an isolated DNA selected from the group consisting of:
- (a) cDNA clones having a nucleotide sequence derived from the coding region of SEQ ID NO:1:
- (b) isolated DNA capable of hybridization to a clone of (a) under moderately stringent conditions and which encode biologically active IgA Fc receptor protein;
- and
- (c) isolated DNA which is degenerate as a result of the genetic code to the DNA defined in (a) or (b) and which encodes biologically active IgA Fc receptor protein.
1 more element
An isolated, substantially homogeneous, biologically active soluble mammalian IgA Fc receptor, wherein the soluble receptor is encoded by an isolated DNA selected from the group consisting of:
- (a) cDNA clones having a nucleotide sequence derived from the extracellular region of SEQ ID NO:1;
- (b) isolated DNA capable of hybridization to a clone of (a) under moderately stringent conditions and which encode biologically active IgA Fc receptor protein;
- and
- (c) isolated DNA which is degenerate as a result of the genetic code to the DNA defined in (a) or (b) and which encodes biologically active IgA Fc receptor protein.
1 more element
Dependencies are inferred from the claim text.