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US 5,328,925 AGranted
Piperidine compounds and their use
AssigneeNovo Nordisk A/S
InventorsPer Sauerberg, Preben H. Olesen
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Abstract
The present invention relates to therapeutically active piperidine compounds, a method of preparing the same and to pharmaceutical compositions comprising the compounds. The novel compounds are useful as stimulants of the cognitive function of the forebrain and hippocampus of mammals and especially in the treatment of Alzheimer's disease, severe painful conditions and glaucoma.
Claims8
A compound of formula I ##STR12## wherein R is H, C.sub.1-3 -alkyl, C.sub.3-4 -cycloalkyl, C.sub.2-4 -alkenyl or C.sub.2-4 -alkynyl;
- and
- R.sup.1 is H, --C.sub.1-3 -alkyl-C.sub.3-5 -cycloalkyl, --OH, OC.sub.2-4 -alkenyl, --OC.sub.2-4 -alkynyl, --OC.sub.3-5 -cycloalkyl or --OC.sub.1-3 -alkyl-C.sub.3-5 -cycloalkyl;
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.