Oxido reductase enzyme system obtained from P. chrysogenum
AssigneeGist-Brocades N.V.
InventorsYair Aharonowitz, Lucia H. M. van der Voort, Gerald Cohen, Roelof A. L. Bovenberg, Rachel Schreiber, Anat Argaman, Yossef Av-Gay, Helena M. Nan, Alfred Kattevilder, Harriet Palissa, Henk van Liempt
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Abstract
A new oxido reductase enzyme activity obtainable from P. chrysogenum, involved in the production of .beta.-lactams, the set of genes encoding said enzyme activity, and a method to enhance said production by using the above-mentioned oxido reductase system and other oxido reductase systems or genes encoding for the same have been disclosed.
Claims4
An oxido reductase system from Penicillium chrysogenum, comprising in isolated form as first and second components two polypeptides, a high molecular weight (HMW) polypeptide with a molecular weight of about 36 kDa and a low molecular weight (LMW) polypeptide with a molecular weight of about 12 kDa, wherein said oxide reductase system reduces disulfide compounds in the presence of a reduced electron carrier.
Dependencies are inferred from the claim text.