Specific DNA molecular probes for Bos-type male genome
AssigneesInstitut National de la Recherche Agronomique (INRA), Institut Pasteur, Commissariat a l'Energie Atomique
InventorsColin Bishop, Corinne Cotinot, Marc Fellous, Marek Kirszenbaum, Marcel Vaiman
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Abstract
Synthetic oligonucleotides of 17 or more consecutive nucleotides of the 49 bases of formula (A) to be used as molecular probes for sexing the embryos or foetuses of ruminant mammals or as molecular probes for detecting a Y chromosome in a spermatozoid population of ruminant mammals of the Bos genus and their use in process of amplification and hybridization assays.
Claims6
A synthetic oligonucleotide selected from the group consisting of a 49 base sequence of nucleotides of formula (A) below:
- ##STR10## and fragments thereof consisting of 17 or more consecutive bases of sequence A.
A synthetic oligonucleotide selected from the group consisting of oligonucleotides having the formulae (1) to (8) below:
- ##STR11## as well as oligonucleotides that are 17 bases long and fully complementary.
A synthetic oligonucleotide selected from the group consisting of oligonucleotides having the formulae (9) to (11) below:
- ##STR12## as well as oligonucleotides that are 20 bases long and fully complementary.
Dependencies are inferred from the claim text.