Method of x-ray imaging using iodinated aromatic propanedioates
AssigneeSterling Winthrop Inc.
InventorEdward R. Bacon
Life of this patent
Estimating the term…
Abstract
Compounds having the structure ##STR1## wherein (Z--COO is the residue of an iodinated aromatic acid; R.sup.1 and R.sup.2 are independently alkyl, fluoroalkyl, cycloalkyl, aryl or aralkyl; and R.sup.3 is H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, cyano, sulfonate, carboxamido, sulfonamido, CO.sub.2 -alkyl, CO.sub.2 -aryl or CO.sub.2 -aralkyl; are useful as contrast agents in x-ray imaging compositions and methods.
Claims6
A method for medical x-ray diagnostic imaging which comprises administering to the body of a mammal a contrast effective amount of an x-ray contrast composition comprising a compound having the structure ##STR11## wherein (Z--COO is the residue of an iodinated aromatic acid;
- R.sup.1 and R.sup.2 are independently alkyl, fluoroalkyl, cycloalkyl, aryl, or aralkyl;
- and
- R.sup.3 is H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, cyano, sulfonate, carboxamido, sulfonamido, CO.sub.2 -alkyl, CO.sub.2 -aryl, or CO.sub.2 -aralkyl.
Dependencies are inferred from the claim text.