Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
AssigneeAllergan, Inc.
InventorsCharles Gluchowski, Michael E. Garst, James A. Burke, Larry A. Wheeler
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AssigneeAllergan, Inc.
InventorsCharles Gluchowski, Michael E. Garst, James A. Burke, Larry A. Wheeler
Estimating the term…
A method of treating a mammal comprises administering to a mammal an effective amount to provide a reduction inflammation in the mammal of a compound selected from the group consisting of those having the formula: ##STR1## pharmaceutically acceptable acid addition salts thereof and mixtures thereof, wherein R.sub.1 and R.sub.4 are independently selected from the group consisting of H and alkyl radicals having 1 to 4 carbon atoms; the R.sub.2 s are independently selected from H or alkyl radicals having 1 to 4 carbon atoms or are, together, oxo; the R.sub.3 s are independently selected from H or alkyl radicals having 1 to 4 carbon atoms or are, together, oxo; the 2-imidazolin-2-ylamino group may be in any of the 5-, 6, 7- or 8- positions of the quinoxaline nucleus; and R.sub.5, R.sub.6 and R.sub.7 each is located in one of the remaining 5-, 6-, 7- or 8- positions of the quinoxaline nucleus and is independently selected from the group consisting of Cl, Br, H and alkyl radicals having 1 to 3 carbon atoms.
A method of treating a mammal for a reduction in inflammation comprising administering to a mammal an effective amount of a compound selected from the group consisting of those having the formula ##STR6## , pharmaceutically acceptable acid addition salts thereof and mixtures thereof, wherein R.sub.1 and R.sub.4 are independently selected from the group consisting of H and alkyl radicals having 1 to 4 carbon atoms;
Dependencies are inferred from the claim text.