Preservative system for ophthalmic and contact lens solutions and method for cleaning disinfecting and storing contact lenses
AssigneeSherman Pharmaceuticals, Inc.
InventorGuy J. Sherman
Life of this patent
Estimating the term…
Abstract
A system and method for cleaning, disinfecting, storing and wetting rigid gas permeable contact lenses is provided. The system includes a cleaning, disinfecting and storing solution and a separate wetting solution. Both solutions contain hydrophilic disinfectants or preservatives which do not inhibit proper wetting of rigid gas permeable contact lenses. The lenses are stored in the cleaning, disinfecting and storing solution during nonwearing periods. This storage also acts as a secondary or backup cleaning treatment to help remove any residual contaminants after the primary cleaning with this solution.
Claims45
A method of treating a contact lens comprising storing the lens during non-wearing periods in a non-abrasive aqueous cleaning solution comprising a disinfectant present in an effective amount for maintaining the sterility of the cleaning solution and for disinfecting the lens as a result of storage therein and a non-abrasive cleaning compound present in an effective amount for cleaning the lens, wherein said disinfectant comprises high purity benzyl alcohol.
A method of treating a contact lens comprising:
- storing the lens during non-wearing periods in a non-abrasive aqueous cleaning solution comprising a disinfectant present in an effective amount for maintaining the sterility of the cleaning solution and for disinfecting the lens as a result of storage therein and a non-abrasive cleaning compound present in an effective amount for cleaning the lens;
- and
- wetting the lens after storage in said cleaning solution with a wetting solution comprising a wetting component and a preservative component wherein said preservative component of said wetting solution comprises high purity benzyl alcohol.
A cleaning, disinfecting, storing and wetting solution system for contact lenses comprising a nonabrasive sterile aqueous cleaning, conditioning and storing solution and a separate sterile aqueous wetting solution,
- (a) said sterile aqueous cleaning, disinfecting and storing solution for contact lenses comprising:
- (i) a hydrophilic disinfectant component consisting of effective amounts of high purity benzyl alcohol and a water soluble salt of ethylenediaminetetraacetic acid for maintaining the sterility of the cleaning, disinfecting and storing solution and for disinfecting contact lenses;
- (ii) at least one cleaning component present in an effective amount for cleaning the contact lens;
- and
- (iii) less than about one ppm by weight of benzaldehyde by total weight of said cleaning, disinfecting and storing solution;
- and
- (b) said sterile aqueous wetting solution comprising:
- (i) at least one wetting agent for contact lenses, present in an effective amount for wetting;
- (ii) a hydrophilic disinfectant component comprising effective amounts of high purity benzyl alcohol and a water soluble salt of ethylenediaminetetraacetic acid for maintaining the sterility of said wetting solution;
- and
- (iii) less than about one ppm by weight benzaldehyde by total weight of said wetting solution.
A method of treating and caring for a rigid gas permeable contact lens with first and second nonabrasive aqueous solutions, comprising:
- (a) cleaning the rigid gas permeable lens with said first aqueous solution, which solution is a cleaning solution and consists of a disinfectant comprising high purity benzyl alcohol and a water soluble salt of EDTA, present in effective amounts for maintaining the sterility of said first solution and for disinfecting a contact lens as a result of storage therein, an alkylarylpolyether alcohol non-ionic detergent and an amphoteric surface active agent, present in effective amounts for cleaning the rigid gas permeable contact lens to allow wetting by said second aqueous solution and less than about one ppm benzaldehyde by total weight of the first aqueous solution;
- and thereafter
- (b) wetting the rigid gas permeable contact lens with said second aqueous solution that comprises a hydrophilic disinfectant system present in an effective amount for maintaining the sterility of said second solution and at least one wetting agent, present in an effective amount for wetting the lens, said disinfectant system consisting of high purity benzyl alcohol and a water soluble salt of ethylenediaminetetraacetic acid and less than about one ppm benzaldehyde by weight of the wetting solution.
A method of caring for a contact lens comprising:
- (a) manually cleaning the contact lens with an aqueous non-abrasive cleaning solution containing at least one cleaning component for contact lenses;
- and
- (b) storing the contact lens in the aqueous non-abrasive cleaning solution during a non-wearing period.
A preserved ophthalmic drug solution comprising an aqueous ophthalmic drug solution and high purity benzyl alcohol, present in an effective amount for maintaining the sterility of the ophthalmic solution and the ophthalmic solution containing less than one ppm by weight of benzaldehyde by total weight of the ophthalmic solution.
A non-abrasive cleaning, disinfecting and storing solution for contact lenses comprising:
- (a) a hydrophilic disinfectant component consisting of effective amounts of high purity benzyl alcohol and a water soluble salt of ethylenediaminetetraacetic acid for maintaining the sterility of the cleaning, disinfecting and storing solution and for disinfecting contact lenses;
- (b) at least one cleaning component present in an effective amount for cleaning the contact lens;
- and
- (c) less than about one ppm by weight of benzaldehyde by total weight of said cleaning, disinfecting and storing solution.
A sterile aqueous contact lens wetting solution comprising:
- (a) at least one wetting agent for contact lenses, present in an effective amount for wetting;
- (b) a hydrophilic disinfectant component comprising effective amounts of high purity benzyl alcohol and a water soluble salt of ethylenediaminetetraacetic acid for maintaining the sterility of said wetting solution;
- and
- (c) less than about one ppm by weight benzaldehyde by total weight of said wetting solution.
A cold disinfecting aqueous solution especially suited for soft contact lenses comprising high purity benzyl alcohol and a water soluble salt of EDTA, present together in effective amounts for disinfecting a contact lens by storage therein.
A composition for preserving the sterility of a contact lens solution comprising high purity benzyl alcohol having a benzaldehyde concentration of less than 100 ppm by weight of benzyl alcohol and a water soluble salt of EDTA.
Dependencies are inferred from the claim text.