Tricyclic heterocycles
AssigneeImperial Chemical Industries PLC
InventorsJohn Oldfield, Howard Tucker
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AssigneeImperial Chemical Industries PLC
InventorsJohn Oldfield, Howard Tucker
Estimating the term…
The invention relates to tricyclic heterocycles of the formula I ##STR1## wherein X is oxy, thio, sulphinyl, sulphonyl, amino, (1-4C)alkylamino or methylene; Y is carbonyl or methylene; each R.sup.1 includes hydrogen, halogeno and various other substituents; each of m and n is 1 or 2; A.sup.1, alkylene, alkenylene or alkynylene; Het is a 5 or 6 membered heteroaryl group optionally bearing particular substituents; and G is carboxy, 1H-tetrazol-5-yl or a group of the formula: --CONH--SO.sub.2 R.sup.2 wherein R.sup.2 is (1-4C)alkyl, benzyl or phenyl; and pharmaceutically-acceptable salts thereof, which possess anti-hyperalgesic properties. The invention also relates to processes for the manufacture of said tricyclic heterocycles; and to novel pharmaceutical compositions containing them.
A compound of the formula I
Dependencies are inferred from the claim text.